President Donald Trump's trade negotiators enter the latest round of NAFTA talks under growing pressure inside their own country to step back from a confrontational stance that's left the U.S. isolated at the negotiating table.

The fourth round of talks to update the North American Free Trade Agreement began Wednesday in the Washington area. Trump has maintained his threat to walk out, even amid rising opposition at home to his hardline stance. On the eve of talks, the top U.S. business group pledged to fight to preserve the pact, while a Congressional committee said it was committed to successful talks and Mexico signaled it can live without the accord.

“There is life after NAFTA,” Mexican Economy Minister Ildefonso Guajardo said Tuesday in an interview with Radio Formula. Mexico could leave NAFTA and have the strength to move on without any serious long-term structural damage to the economy, he said.